Prilocaine Hydrochloride Local Anesthetic Powder Prilocaine HCL For Rain Relief 1786-81-8

Place of Origin: Guangdong,China (Mainland)
Brand Name: Jiazhinuo
CAS No.: 23239-88-5
Purity: 99
Appearance: liquid
Payment Terms: Western Union, MoneyGram, T/T
Delivery Time: Prompt after payment

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Product Description

Payment & Shipping Terms Supply Capacity
Unit Price:1.0 USDProduction Capacity:1000t/month
Trade Term:FOB,CFR,CIFPacking:discreet packing
Payment Terms:Bitcoin, T/T, WU, Money GramDelivery Date:ASAP
Min. Order:10 Gram
Means of Transport:Ocean, Air, Land

Prilocaine Hydrochloride Pharmaceutical Intermediates Prilocaine HCL For Rain Relief 1786-81-8 Local Anesthetic Powder


Prilocaine HCL Description
  HCL is a local anesthetic of amino amide prepared by Claes Tegner and NilsLöFgren. In its injectable form, it is usually used in dentistry. It is also often used in combination with lidocaine for skin anesthesia (lidocaine / propylamine or EMLA) for the treatment of paresthesia and other diseases. Due to low cardiac toxicity, it is usually used for intravenous anesthesia.
In some patients, metabolites of prilocaine may cause abnormal side effects of methemoglobinemia and can be treated with methylene blue.

Local anesthesia is a substance that causes sensory loss only in its application without affecting consciousness. Most local anesthetic structures have on the other side an amino ester or aminoamide group attached to a hydrophilic (secondary or tertiary amine) and hydrophobic group (aromatic compound). The ester can be hydrolyzed to the p-aminobenzoic   in the plasma by cleavage of the cholinesterase. Amides are stable for long and more systematic distributions. Esters include Novocain, Nesacaine, Pontocaine, Benzocaine and  Amides include sicaine, cabbaine, Citanest, Marcaine, Duranest,

  HCLusage
Praca is a local anesthetic of amino amide. Prilocaine is commonly used in dentistry. Placaine is also often used in combination with lidocaine for skin anesthesia (lidocaine or EMLA) for the treatment of paresthesia and other diseases.

Local anesthesia is a substance that causes sensory loss only in its application without affecting consciousness. Most local anesthetic structures have an amino ester or aminoamide group attached to a hydrophilic (secondary or tertiary amine).

The ester can be hydrolyzed into the plasma in the form of PARA-aminobenzoic  by the enzyme base esterase. Amides are stable for long and more systematic distributions. Esters include prochlorocene, Novos, Nesacaine, Pontocaine, Benzocaine, . Amides include sicaine, cabbaine, Citanest, Bouaine (Marcaine), Etidocaine (Duranest).

The most recommended dose of Placaine HCL


Prilocaine HCL is used in children
Since this is due to age and weight, it is difficult to recommend the maximum dose of any drug for children. For children with normal lean body weight and normal physical development for less than 10 years, the maximum dose can be determined by applying standard pediatric drug preparations (eg, Clark rule). For example, according to the Clark rule, 5-year-old children weigh 50 pounds, according to Clark rules, acetic    dose should not exceed 150 to 200mg (6.6 to 8.8mg / kg or 3 to 4mg / lb body weight)


COA


Product NamePropitocaine hydrochloride
Assay (%)≥ 99.00Cas No.1786-81-8
Flash point:134.3 ° CMelting Point168-170 ° C
Steam pressure2.05E-05mmHg at 25 ° CBoiling point361.6 ° C at 760 mmHg
Loss on drying≤1%
Melting point66-69 ° C
Sulfated ash≤0.1%
Heavy metals≤10ppm
Sulfate≤0.1%
Chloride≤35ppm
2,6-dimethylaniline≤100ppm
StandardUSP/BP
Main FunctionsLocal anesthetic.
GradePharmaceutical raw materials
PackageWhite crystalline powder, odorless, a little bitter
Shelf Life24months
StorageStore in sealed containers at cool & dry place. Keep away from light, moisture





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Category: Local Anesthetics


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